□Yoshihide Hayashizaki
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Representative CEO, K.K. DNAFORM, Representative CEO, K.K. Mirai Genomics,
Chairman & CEO, K.K. SS Dnaform
2-6-29 Tsurumi-chuo, Tsurumi-ku, Yokohama, Kanagawa, 230-0051, Japan
Phone: +81- 45-510-0607
Fax: +81- 45-510-0608
e-mail：yoshihide.hayashizaki@dnaform.jp
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EDUCATION |
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| 1982 | M.D. | Medical faculty of Osaka University, Japan |
| 1986 | Ph.D. | Osaka University, Institute for Molecular and Cellular Biology, Japan |
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MAJOR EMPLOYMENT |
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| 1995-1998 | Project Director, RIKEN genome exploration research project, Japan |
| 1995-2008 | Chief Scientist, Department Director and Chairman, Genome Science Laboratory, RIKEN, Japan |
| 1998-2008 | Project Director, RIKEN Genome Exploration Research Group, Genomic Sciences Center, Japan |
| 2008-2013 | Director, Omics Science Center, RIKEN Yokohama Institute, Japan |
| 2013-2021 | Program Director, RIKEN Preventive Medicine and Diagnosis Innovation Program, Japan |
| 2015-2018 | Advisor to President, RIKEN |
| 2016-2021 | Core Principal Investigator, RIKEN |
| 2021-present | Representative CEO, K.K. Mirai Genomics, K.K. DNAFORM, Chairman & CEO, K.K. SS Dnaform |
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POSITIONS |
| 1995-2010 | Professor, Tsukuba University Medical School |
| 1998-2013 | Professor, Graduate school of Integrated Science, Yokohama City University, Japan |
| 2003-2009 | Guest Professor, University of Queendland, Australia |
| 2003-2011 | Guest Professor, Karolinska Institute, Sweden |
| 2011-present | Scientific Advisory Board Member, Science for Life Laboratory (SciLifeLab), Sweden |
| 2012-2013 | Visiting Scholar, Beijing Genomics Institute (BGI), China |
| 2012-2015 | Board of Trustees, BioBank Qatar, Qatar |
| 2015-present | International Scientific Advisory Committee, (ISAC),Qatar |
| 2015-present | Visiting Professor, Juntendo University, Japan |
| 2015-present | Executive Director, The Japan China Medical Association, Japan |
| 2015-present | Distinguished visiting professor, University at Buffalo, the State University of New York, USA |
| 2016-2018 | Senior Researcher, Research Institute at SFC, Keio University, Japan |
| 2017-present | Committee member, The Japan China Medical Association, Japan, Cooperation Committee |
| 2018-present | Auditor-secretary, Association for Rare Variant Surveillance（RVS) |
| 2019-2019 | Part-time professor, Kyoto University, Japan |
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AWARDS |
| 1995 | Tokyo Techno forum Gold Medal Prize, Japan |
| 2000 | Tsukuba Prize, Japan |
| 2004 | Commendation by the Minister of Education, Culture, Sports, Science and Technology Japan |
| 2005 | NISTEP AWARD 2005, Japan |
| 2007 | Medal with Purple Ribbon, Japan |
| 2010 | Kihara Prize, The Genomics Society Japan |
| 2010 | Mochida Commemoration Science Prize, Japan |
| 2012 | Honorary Doctor of Medicine (MDhc), Karolinska Institute (Sweden) |
| 2013 | Chen Award for Distinguished Academic Achievement in Human Genetic and Genomic
Research（Human Genome Organization: HUGO） |
| 2016 | The Australian Museum, 2016 Eureka Prize for Excellence in International Scientific Collaboration (Australia) |
| 2017 | Symbol of Trust, EIDOS-MEDICINE (Russia) |
| 2017 | The 58th Science and Technology Firm Festival, Excellence Award, Scientific Frontier, Unlocking the Mysteries of Life with RNA |
| 2019 | EMBO Associate Member |
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QUALIFICATIONS |
| Major international experience: |
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General organizer of the international FANTOM1-5 consortium |
| Major scientific achievements: |
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Development of a series of cDNA technologies and its application to establish a mouse genome encyclopedia.
Development of Cap Analysis of Gene Expression (CAGE), gene expression profiling method.
Leading scientist in omics science
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SELECTED PEER-REVIWED PUBLICATIONS (Selected from 575 publications) |
- Kawai J, et al. Functional annotation of a full-length mouse cDNA collection. Nature, 409, 685-690 (2001)
- Okazaki Y, et al. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature, 420, 563-73 (2002)
- Carninci P, et al. The transcriptional landscape of the mammalian genome. Science, 309, 1559-1563 (2005)
- Katayama S, et al. Antisense transcription in the mammalian transcriptome. Science, 309, 1564-1566 (2005)
- Carninci P. et al. Genome-wide analysis of mammalian promoter architecture and evolution. Nature Genetics, 38, 626-635 (2006)
- Suzuki H, et al. The transcriptional network that controls growth arrest and differentiation in a human myeloid leukemia cell line. Nature Genetics, 41, 553-62 (2009)
- Y. Maida, et al. An RNA-dependent RNA polymerase formed by TERT and the RMRP RNA. Nature, 461, 230-235 (2009).
- Ravasi T, et al. An atlas of combinatorial transcriptional regulation in mouse and man. Cell, 140, 744-752 (2010)
- Forrest AR, et al. A promoter-level mammalian expression atlas. Nature, 507, 462-470 (2014)
- Andersson R, et al. An atlas of active enhancers across human cell types and tissues. Nature 507, 455-461 (2014)
- Arner E. et al. Transcribed enhancers lead waves of coordinated transcription in transitioning mammalian cells, Science, 347, 1010-1014 (2015)
- Rackham, O.J. et al. A predictive computational framework for direct reprogramming between human cell types. Nat Genet, 48, 331-335(2016).
- Chung-Chau Hon, et al. An atlas of human long non-coding RNAs with accurate 5’ ends. Nature, 543, 199-204(2017)
- Derek de Rie, et al. The FANTOM5 integrated expression atlas of miRNAs and their promoters.
Nature Biotechnology (2017)
- Hirabayashi, et al. NET-CAGE characterizes the dynamics and topology of human transcribed cis-regulatory elements. Nat Genet, 51, 1369-1379(2019)
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| See also http://fantom.gsc.riken.jp/papers/ |